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Sulforaphane (synthetic)

Therapeutic Category

TECHNICAL PROFILE

Technical name: 1-Isothiocyanato-4-(methanesulfinyl)butane

CAS No: 4478-93-7

Empirical formula: C6H11NOS2

Molecular weight: 177.29 g/mol

 

 

 

ADVANTAGES

Sulforaphane (SFN) is an antioxidant compound contained in cruciferous vegetables such as broccoli, Brussels sprouts and cabbage. Broccoli has the highest concentration of SFN.

SFN is only released upon chewing and digestion of the plant source, when the enzyme myrosinase (only available in the plant source) reacts and transforms its precursor, Glycoraphanin, into Sulforaphane. 

Clinical studies have shown that, at high doses, SFN has cancer- preventive and neuro-protective qualities against breast cancer, prostate cancer, neurodegenerative disorders, multiple sclerosis, diabetes and autism.

SFN also enhances the efficacy of anti-cancer drugs including cisplatin, gemcitabine, doxorubicin, and 5-fluorouracil, toward pancreatic and prostate cancer cells, while limiting their toxicity to normal cells.

SFN has beneficial effects to the skin when it comes to photoaging and sunburn cell formation, by maintain collagen levels and protecting the skin from wrinkling.

 

FEATURES

  • Antioxidant status
  • Natural protection of cells
  • High chemical reactivity
  • Anti-inflammatory effect

BENEFITS

We offer synthetically produced and stabilized sulforaphane that provides several advantages, including API-level quality, lower production cost manufacturing robustness and supply chain security.

 

 

APPLICATION

Active sulforaphane is used in food ingredients & dietary supplements (for adults to support immune system, combat inflammation and promote detoxification), pharmaceutical formulations (to enhance the efficacy of anti-cancer drugs) and skin care products (in ointments for topical anti-inflammatory treatment and anti-dehydration, and in sunscreens for protection from UV radiation).

 

Chemical structure of sulforaphane

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